Osteoarthritis affects almost a quarter of the population of dogs on the planet. It’s a chronic joint disease caused by gradual loss of joint cartilage, new bone formation and thickening of the joint capsule. There are no obvious primary causes for osteoarthritis. It can be related to age and genetics, and some other factors such as obesity, gender, breed, exercise, and diet can sometimes contribute to the development. Even young dogs can be affected, especially large and giant breeds
The most obvious signs of arthritis in dogs include pain, discomfort, stiffness, lameness, bunny-hopping, inability to jump and reluctance to exercise. Most frequently used methods to diagnose the condition are physical exam, x-ray, and less frequently CT (Computer Tomography) and MRA (Magnetic Resonance Imaging).
Natural treatment options
If your dog has been diagnosed with osteoarthritis, it most likely means a lifetime treatment plan. It’s important to opt for products which are natural and completely safe to be used long term. Scientific data reveals no side-effects connected to long-term usage of Antinol.
Since its first appearance on the market in 2018, Antinol quickly became the keystone supplement for the treatment of osteoarthritis in dogs. The product is the latest advancement in canine arthritis management which gives veterinarians a chance to provide safe, effective and versatile long-term treatment option for this chronic disease.
The active ingredient in Antinol is PCSO-524. This is a marine lipid concentrate which is extracted from GLM (green-lipped mussel – Perna canaliculus). It’s not considered to be a drug as Antinol is one hundred percent natural.
Mechanism of action
It’s important to understand just how Antinol helps your furry friend feel more comfortable and live a happy life free of pain.
The supplement is a broad-spectrum anti-inflammatory. All the cells in your pup’s body require various fatty acids in order to function properly. The cells are surrounded by a cell membrane that needs to maintain a proper balance between Omega 3 and Omega 6 fatty acids. The essential fatty acids cannot be produced by the body and must be acquired through the diet.
Once they enter the digestive system, the FA’s are transferred to the cell membranes via the bloodstream. While Omega 6 has pro-inflammatory properties, Omega 3 has anti-inflammatory properties, so maintaining the balance between the two is quite important.
The main precursor for inflammation in the dog’s body is Arachidonic acid which is released by the cell membrane. Once released it transforms into molecules causing inflammation. The transformation is due to enzymes Cox 2 and 5 Lox. The unique mixture of over 90 fatty acid fractions in Antinol works in a way to modulate Cox 2 and 5 Lox and consequently reduce inflammation and pain.
Its mechanism of action slows down cartilage degradation and promotes repair of the cartilage. So Antinol may also used as a preventative treatment for all types of dogs.
Scientific research has shown that Antinol has a synergistic effect with NSAID’s, which are regularly prescribed for canine osteoarthritis. Using a combined therapy the alleviation of symptoms will be much faster and more effective. Dual action with NSAID’s are highly recommended, but should be consulted with a veterinarian.
